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Phages for Global Health

Phages for Global Health facilitates the development of antibacterial phage products for developing countries. Natural Antibacterial Agents: Bacteriophages (phages) are bacteria-killing viruses that exist in the environment, on our food, and in our bodies, and they can be selected to target only specific bacteria while leaving other, helpful bacteria and human cells unharmed. Phages have been used as a standard component of medical practice in certain parts of the world for over 100 years, and they have exhibited remarkable safety and activity profiles. Most notably, phages are active against both antibiotic-resistant and antibiotic-sensitive bacteria -- a crucial feature in the midst of our global antimicrobial resistance crisis. In addition, phages can be easily isolated from contaminated environments, and they are inherently inexpensive to manufacture. It is also possible to dry powder formulate phages such that the final products do not require refrigeration. Taken together, all of these factors make phages particularly well-suited as antibiotic alternatives for developing countries. How We Work: Phages for Global Health brings together international, multidisciplinary teams to co-develop phage products for specific applications in developing countries. To efficiently implement these projects, we build partnerships between global phage experts and developing world infectious disease specialists (clinicians, food safety scientists, regulatory advisors, and stakeholder engagement professionals). With this mix of specialists, we create teams that have both the technical expertise necessary to develop phage products and also the local scientific and cultural knowledge to deliver products that will be socially accepted and effective. Our growing consortium of project partners includes leaders from non-profit organizations, for-profit companies, and academic and governmental institutions across Africa, Europe and North America. In addition to bringing together these teams, Phages for Global Health helps develop the overall project strategies, advises on product development, supplies project management, and leads fundraising efforts. Together with our partners, we have also created a series of short-term laboratory training programs to teach key essentials of phage biology to scientists in developing countries. Our Current Projects: For our projects we identify bacterial diseases that have significant gaps in prevention or treatment tools and for which there is already strong data indicating that phages can help. And we work in countries where we have partnerships with leading public health scientists who are able to substantively impact standard practices in their countries. Our existing projects are summarized below, and we are in discussions with specialists around the world through which additional projects may soon emerge. (1) Cholera Phages: (Democratic Republic of the Congo / DRC) Developing cholera phage products that can be used both for preventative treatment in people and for water decontamination. Partners: Ministry of Health (DRC), University of Kinshasa (DRC), Yale University (US), University of Alberta (Canada), Queen Astrid Military Hospital (Belgium) (2) Campylobacter Phages: (Kenya & Egypt) Developing Campylobacter phage products to decontaminate retail poultry meat, which is the primary source of Campylobacter infection in people. Partners: Kenya Medical Research Institute, University of Nairobi (Kenya), University of Science and Technology (Egypt), University of Nottingham (UK), University of Alberta (Canada) (3) Laboratory Training Program: (East Africa) Delivering a 2-week, hands-on laboratory training course through which African scientists can learn how to isolate and characterize phages in their own regions. Partners: University of Nairobi (Kenya), Sokoine University of Agriculture (Tanzania), Makerere University (Uganda), Yale University (US), University of Utah (US)

Harrisburg River Rescue And Emergency Services Inc

As a result of the dedication of their volunteer river rescue personnel, they are proud to provide water safety education and training for the community and professional rescue personnel, water rescue and emergency response, ice rescue, and emergency boat operations for municipalities and organizations through Dauphin County.

Fountains Of Hope International

Fountains of Hope serves God by providing life-giving, safe water solutions to people in need.

Etta Projects

Etta Projects collaborates with communities, creating sustainable solutions to improve health, sanitation and clean water.

Global Care Alliance Inc

PROVIDING RELIEF IN THE FORM OF FOOD, HOUSING, WATER AND MEDICAL CARE TO THE PEOPLE OF THE POOREST COUNTRIES IN OUR WORLD

IMPACT LAOS

Mission: To make an impact on the people of Laos by providing humanitarian aid in the following areas: Medical and Dental Clinical Outreach Water Wells School Renovations Education: School Supplies and Activities Sports: Equipment, Uniforms Local Infrastructure; Co-op Farm, Rice Barn, Water Plumbing Alcohol and Drug Recovery

Mainspring Conservation Trust

Located in the heart of the Southern Blue Ridge, the mission of Mainspring Conservation Trust (formerly the Land Trust for the Little Tennessee) is to conserve the waters, forests, farms and heritage of the Upper Little Tennessee and Hiwassee River Valleys. We are dedicated to three core initiatives: conserve the land, restore the water, and connect the people to these valuable resources.

Catis Mexico

Promoting healthier more prosperous lives through practical sustainable solutions along the pathways water travels through our lives and the planet. We help communities at risk in Central Mexico confront environmental challenges—access to safe healthy water supplies most of all. We collaborate with technology innovators and social organizations to develop innovative, open-source solutions that address the diverse challenges of water quality and access, and positively impact communities beyond our borders through training and sustainable enterprise development programs.

Blue Missions Group

To connect families with access to clean water and sanitation while cultivating a generation of global citizens through service-driven travel.

Jah Works

We promote community sustainability by enabling better access to clean water, healthy food, relevant education and equitable job opportunities.

Well Aware Inc

Well Aware is a 501(c)3 nonprofit that funds and implements sustainable clean water systems to drive economic development and empower communities in East Africa.

Alaska Dive Search Rescue And Recovery Team

The Alaska Dive Search, Rescue and Recovery Team (AK Dive Rescue) is an all-volunteer, unpaid, 501(c)(3) non-profit public safety water rescue/dive search and recovery, team that exists to provide the Department of Public Safety (DPS) a statewide capability above and underneath the waters surface. The team is activated by the State Search and Rescue Coordinator and is ready to deploy for recovery missions anywhere in Alaska usually within two hours of notification.