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The Trevor Project is the world’s largest suicide prevention and crisis intervention organization for LGBTQ+ (lesbian, gay, bisexual, transgender, queer, and questioning) young people. The organization works to save young lives by providing support through free and confidential suicide prevention and crisis intervention programs on platforms where young people spend their time: a 24/7 phone lifeline, chat, and text. The organization also runs TrevorSpace, the world’s largest safe space social networking site for LGBTQ youth, and operates innovative education, research, and advocacy programs.

The mission of Wounded Warrior Project® (WWP) is to honor and empower wounded warriors. The organization's vision is to foster the most successful, well-adjusted generation of injured service members in our nation’s history, by CONNECTING, SERVING, and EMPOWERING the wounded men and women who so bravely volunteered to serve our nation on or after the events of September 11, 2001. They CONNECT warriors, their families, and caregivers to peers, programs, and communities to ensure they have a readily available network of support. SERVE by providing free mental and physical health and wellness programs, career and benefits counseling, and by providing ongoing support for the most severely injured. And EMPOWER warriors to live life on their own terms, mentor fellow veterans and service members, and embody the WWP logo by carrying one another on a path toward recovery. Today, more than 110,000 wounded warriors and 26,000 family support members and caregivers are registered with WWP and have access to free programs and services that CONNECT, SERVE, and EMPOWER.

Project C.U.R.E. was founded in 1987 to help bridge staggering health resource gaps in the developing world by matching medical supplies and modern equipment with facilities in need to empower doctors and nurses with the tools they need to treat disease, deliver vaccines, perform life-changing surgeries and ensure safe childbirth. Project C.U.R.E. operates distribution centers in Colorado, Tennessee, Texas and Arizona and receives donations of supplies and specialized equipment from hundreds of U.S. hospitals and medical manufacturers. Thanks to the dedication of thousands of volunteers nationwide, two to three cargo containers of life-saving aid leave Project C.U.R.E.’s warehouses every week. In addition, Project C.U.R.E. sends volunteer medical teams to underserved facilities abroad to provide free care and train local healthcare staff. Today, Project C.U.R.E. is the world’s largest distributor of medical donations to resource-limited communities across the globe, touching the lives of patients, families and children in 130 countries.

Our mission is to place power in the hands of local health care workers to save lives across the globe. We are a global health and humanitarian relief organization, committed to transforming lives and uplifting communities by empowering healthcare workers to expertly implement and teach innovative lifesaving solutions, in times of need and into the future.

The Hendren Project (THP) mission is to provide sponsor-supported digital resources that enable a global pediatric surgical community to help one another better serve children with complex surgical issues throughout their lives. The digital resources are provided to THP members without charge through the THP website.

Women's Global Education Project (WGEP) believes that universal education, gender equality and empowerment of women are critical to a society's development. Our mission is to empower women and girls in rural regions of Sub-Saharan Africa through education to build better lives and foster more equitable communities

Parent Project Muscular Dystrophy fights to end Duchenne. We accelerate research, raise our voices to impact policy, demand optimal care for every single family, and strive to ensure access to approved therapies.

The mission of Project Salone is to care for the orphan and widow and advocate for the voiceless. Project Salone will raise awareness of the orphan crisis and directly aid orphans and impoverished families to create a sustainable future.

Project*Biome exists to catalyze ecological healing within the elemental biospheres of the planet: land, water, and air. Project*Biome envisions humanity consciously reintegrated with the natural systems of the Earth as a keystone to the restoration of our health and vitality

Project Periwinkle's mission is to bring awareness to and fund medical research for stomach cancer.