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The mission of the Cancer Foundation is to ensure superior cancer care for all residents of Santa Barbara County regardless of means. To this end, the Foundation is the leading non-profit fundraising and grant making institution dedicated to cancer care in Santa Barbara County. The Cancer Foundation is the largest donor to Ridley-Tree Cancer Center, the leading provider of cancer care on the central coast.

The Foundation's mission is to Detect, Treat, Educate, and Eliminate breast cancer: To raise and award funds for breast cancer detection, for breast cancer treatment, for education on the importance of early and regular screenings, and for research to eliminate the disease. Approximately 90% of the Foundation's grants will continue to be granted to charities and non-profits in Fauquier and Loudoun counties, with the other 10% to regional research.

Bear Necessities Pediatric Cancer Foundation is a national organization with a mission to eliminate pediatric cancer and to provide hope and support to those who are touched by it.

The mission of the William Guy Forbeck Research Foundation is to promote advances in the field of oncology, particularly pediatric oncology, by shortening the cancer research timetable.

4Him2Day-Children's Cancer Resource Foundation provides support to families in the greater Willamette Valley in treatment for childhood cancer through financial assistance, physical acts of service and emotional support.

The mission of the Samuel Waxman Cancer Research Foundation is to eradicate cancer by funding cutting-edge research that identifies and corrects abnormal gene function that causes cancer and develops minimally toxic treatments for patients.

Cancer Guide Research Foundation (CGRF) partners with research institutions, healthcare organizations, cancer and caregiver communities, doctors, scientists, and students to work towards helping patients understand and treat their cancer while also empowering patients by providing needed information and hope for the future.