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The Foundation's mission is to raise funds that advance scientific research into the causes, treatments and prevention of ALS; provide people living with ALS, their families and caregivers exceptional clinical care and support services; and increase awareness and eduction of ALS.

As the Drug Discovery Engine for ALS, the ALS Therapy Development Institute (ALS TDI) discovers and invents ALS treatments and partners to advance them into clinical trials. It is the first and largest nonprofit biotech focused 100% on ALS research. ALS TDI incorporates all aspects of drug discovery under one roof to find treatments as quickly as possible. Located in Watertown, MA, ALS TDI employs researchers with over 300 years of combined experience and expertise across all areas of drug discovery. ALS TDI is recognized as an international leader in preclinical and translational ALS research, and partners with pharmaceutical companies and biotechs around the world. Awarded the highest nonprofit rating – four stars – on Charity Navigator, ALS TDI spends 87 cents of every dollar raised on finding effective treatments and cures for ALS.

Hospice of Michigan's mission is to ensure quality of life and a comfortable, peaceful death for all patients receiving our care, and provide support for their loved ones. We will serve everyone in our communities who needs and seeks our care and strive to improve the state of end-of-life care.

The Hendren Project (THP) mission is to provide sponsor-supported digital resources that enable a global pediatric surgical community to help one another better serve children with complex surgical issues throughout their lives. The digital resources are provided to THP members without charge through the THP website.

Established in the year 2000, the Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices.

From the website: "We are the only Hong Kong charity dedicated to gynaecological cancers. The Karen Leung Foundation’s mission is to save lives by reducing the impact of gynaecological cancers in Hong Kong. We envision a world where women have every opportunity to live healthy and fulfilling lives free from gynaecological cancers."

Our mission is a preferential option for the poor in health care. By establishing long-term relationships with sister organizations based in settings of poverty, Partners In Health strives to achieve two overarching goals: to bring benefits of modern medical science to those most in need of them and to serve as an antidote to despair. We draw on the resources of the world's leading medical and academic institutions and on the lived experience of the world's poorest and sickest communities. At its root, our mission is both medical and moral. It is based on solidarity, rather than charity alone. When our patients are ill and have no access to care, our team of health professionals, scholars, and activists will do whatever it takes to make them well- just as we would do if a member of our own families, or we ourselves, were ill.

The mission of the Lung Cancer Research Foundation is to support national research studies and activities focused on developing innovative strategies for better treatments, screening, and prevention of all cancers of the lung. New knowledge gained by funding scientific and clinical research initiatives will lead to more positive outcomes and improved quality of life for all lung cancer patients.

“Maanavseva" (Service to Humans) is a Registered Non-Profit with a mission to fight malignancies including breast cancer among rural women in Indian villages. The mission is achieved through activities such as educating, creating awareness, conducting preventive examinations and mammogram screenings and facilitating the hand-holding of rural women with necessary follow-up and treatment.Maanavseva intends to implement this mission by adopting one village at a time and conducting 100% screening of all village women as per the health guidelines and implement follow-up on a sustained basis. The short term focus is to create a successful process for a cluster of villages that is replicable and sustainable. Maanavseva will achieve this goal through conducting pilot studies in villages, identify, resolve and document the challenges involved and arrive at a workable and sustainable model. The long term focus is to expand the model to several clusters of villages through sponsorship of corporations, local bodies and other Governmental Schemes. Most prevalent cancers for rural women can be cured by early detection and appropriate treatment. If these cancers are detected early, the cost is less, treatment is less invasive, survival rates are higher and the quality of life is better. Therefore we believe that by creating awareness about these cancers and early detection through mammogram and other screenings is extremely important and is the only way to win the war on breast cancer.

Families are at the heart of MDA's mission. We wake up every morning to create more hope and answers for families living with muscular dystrophy and related diseases that take away physical strength and mobility. We do this by finding research breakthroughs across diseases, caring for kids and adults from day one and empowering families with services and support in hometowns across America.

Crohn's disease and ulcerative colitis are collectively known as inflammatory bowel disease (IBD) because they cause severe inflammation of the intestinal tract, and have common symptoms. The cause remains unknown, and there is no medical cure. The Crohn's & Colitis Foundation of America was founded in 1967. Its mission is to find a cure for Crohn's disease and ulcerative colitis and to improve the quality of life of children and adults affected by these diseases.

Smile Train is an international children’s charity with a sustainable approach to a single, solvable problem: cleft lip and palate. Millions of children in developing countries with unrepaired clefts live in shame, but more importantly, have difficulty eating, breathing and speaking. Cleft repair surgery is simple, and the transformation is immediate. Our sustainable model provides training and funding to empower local doctors in 85+ developing countries to provide 100%-free cleft repair surgery in their communities. We use the “teach a man to fish” model focusing on training local doctors to perform cleft repairs in their communities. Those doctors then go on to train other doctors creating a long-term, sustainable system. Patients see their smile for the first time, parents cry tears of joy, lives and communities are changed forever. As a result of our efficiency and with the support of our donors and partners around the world, Smile Train has transformed the lives of more than one million children by giving them the power of a smile -- that's roughly 350 surgeries a day and 128,000+ every year.