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Little City is dedicated to serving children and adults with intellectual and developmental disabilities by providing the best options and opportunities to live safely, learn continuously, explore creatively and work productively throughout their lifetime. By inspiring, advocating and pursuing success with passion and purpose, lives are changed through hope, happiness, and optimism.

Our mission is to find a effective treatments and ultimately a cure for fragile X syndrome, the most common inherited cause of autism. We directly fund research grants and fellowships at top universities around the world. FRAXA was founded in 1994 by three parents of children with fragile X. Fragile X Syndrome is the most common inherited cause of autism and intellectual disabilities. It affects 1 in 4000 boys and 1 in 6000 girls worldwide, and one in 260 women and 1 in 800 men are carriers. Treatments for fragile X are likely to help people affected by related disorders including autism, Alzheimers, and many other brain disorders.

Our mission is to facilitate, advocate and promote education, support and research for the prevention, treatment and cure of liver disease.

OMF’s mission is to accelerate and enhance scientific research, advocacy, and awareness of ocular melanoma and to provide education and support to patients, their families, and healthcare professionals. For patients and their loved ones, OMF aspires to be the top destination for up-to-date OM-related educational information, a meeting place, and advocacy resource. For doctors and researchers, OMF strives to be the connective tissue, facilitating interdisciplinary cancer research. The goal of OMF is to have there exist accessible and effective treatments for ocular melanoma and, one day, a cure

Mission: To facilitate global collaboration and fund world-class research, medical education, and treatment trials, that make a positive impact on the lives of people with ME/CFS, Long COVID and related diseases. Vision: Significantly improve patient outcomes while advancing a cure. Goals: Our primary goals are to: frame clear disease mechanisms and models; find effective treatments and diagnostic markers; increase accurate diagnoses; and ensure access to quality care.

The Foundation Fighting Blindness, Inc. is the world’s leader in providing awareness and funding that drives the research that will provide preventions, treatments and cures for people affected by retinal degenerative diseases.

The mission of the Alzheimer’s Foundation of America (AFA) is to provide support, services and education to individuals, families and caregivers affected by Alzheimer’s disease and related dementias nationwide, and fund research for better treatment and a cure.

The Foundation's mission is to raise funds that advance scientific research into the causes, treatments and prevention of ALS; provide people living with ALS, their families and caregivers exceptional clinical care and support services; and increase awareness and eduction of ALS.

National Breast Cancer Foundation's (NBCF) mission is to save lives through early detection and to provide mammograms for those in need.Our mission includes increasing awareness through education, providing diagnostic breast care services for those in need, and providing nurturing support services.

The mission of the Lung Cancer Research Foundation is to support national research studies and activities focused on developing innovative strategies for better treatments, screening, and prevention of all cancers of the lung. New knowledge gained by funding scientific and clinical research initiatives will lead to more positive outcomes and improved quality of life for all lung cancer patients.

The Multiple Myeloma Research Foundation, Inc. mission is to: relentlessly pursue innovative means that accelerate the development of next-generation multiple myeloma treatments to extend the lives of patients and lead to a cure. To achieve this purpose, four goals are pursued: Funding research in the field of multiple myeloma, building collaborations among researchers and industry, providing disease and treatment related information to patients and family members while advocating for optimal patient care, and raising awareness of multiple myeloma.

The Lupus Foundation of America (LFA) is the oldest and largest national nonprofit voluntary health organization focused on improving the quality of life for people with lupus. Our unique dual mission serves the ongoing needs of people affected by lupus today while leading efforts to find a cure – from care to cure!  Through the national office in Washington, DC and a nationwide network of chapters, offices, support groups and community representatives, the LFA conducts programs of research, education, and advocacy.  The LFA is leading efforts to bring national attention and resources to bear upon lupus in order to shine a light on this medically underserved disease, accelerate the pace of medical research on lupus, build support for the needs of those affected by lupus, and elevate lupus to a place of prominence on the nation’s health care agenda.