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The Foundation's mission is to raise funds that advance scientific research into the causes, treatments and prevention of ALS; provide people living with ALS, their families and caregivers exceptional clinical care and support services; and increase awareness and eduction of ALS.

The mission of Hearing Health Foundation (formerly called Deafness Research Foundation) is to prevent and cure hearing loss through ground breaking research.

Our Mission: To partner with the ALS community as we drive the discovery of prevention strategies, treatments, and cures for ALS; provide access to quality care and connection; and promote initiatives to improve health outcomes.

The mission of The Foundation is to empower lives for a brighter future by facilitating projects and partnerships that enhance the welfare, education, health, and artistic and athletic abilities of individuals with Down syndrome.  The vision of The Foundation is to create an environment where people with Down syndrome are included in every facet of the community.  We believe that every person has something to offer regardless of their abilities.  It is our hope to enable people with Down syndrome to become integrated into all areas of their lives beginning with school, through college and meaningful employment.

Guide Dogs for the Blind provides enhanced mobility to qualified individuals through partnership with dogs whose unique skills are developed and nurtured by dedicated volunteers and a professional staff. Established in 1942, Guide Dogs for the Blind continues its dedication to quality student training services and extensive follow-up support for graduates. Our programs are made possible through the teamwork of staff, volunteers and generous donors. Services are provided to students from the United States and Canada at no cost to them.

Little City is dedicated to serving children and adults with intellectual and developmental disabilities by providing the best options and opportunities to live safely, learn continuously, explore creatively and work productively throughout their lifetime. By inspiring, advocating and pursuing success with passion and purpose, lives are changed through hope, happiness, and optimism.

METAvivor is dedicated to the specific fight of women and men living with stage 4 metastatic breast cancer. At the time of METAvivor’s founding, no organization was dedicated to funding research for the disease and no patient groups were speaking out about the dearth of stage 4 cancer research. While more and more people have taken up the cry for more stage 4 research, METAvivor remains the sole US organization dedicated to awarding annual stage 4 breast cancer research.

As the Drug Discovery Engine for ALS, the ALS Therapy Development Institute (ALS TDI) discovers and invents ALS treatments and partners to advance them into clinical trials. It is the first and largest nonprofit biotech focused 100% on ALS research. ALS TDI incorporates all aspects of drug discovery under one roof to find treatments as quickly as possible. Located in Watertown, MA, ALS TDI employs researchers with over 300 years of combined experience and expertise across all areas of drug discovery. ALS TDI is recognized as an international leader in preclinical and translational ALS research, and partners with pharmaceutical companies and biotechs around the world. Awarded the highest nonprofit rating – four stars – on Charity Navigator, ALS TDI spends 87 cents of every dollar raised on finding effective treatments and cures for ALS.

OUR MISSION LUNGevity Foundation is firmly committed to making an immediate impact on increasing quality of life and survivorship of people with lung cancer by accelerating research into early detection and more effective treatments, as well as providing community, support, and education for all those affected by the disease. OUR VISION A world where no one dies of lung cancer. OUR VALUES We believe it's important for our board, our staff, and our constituents to know the values that drive all our actions. We are: FOCUSED ON SURVIVORSHIP 100% dedicated to increasing and improving lung cancer survivorship RESULTS-ORIENTED Always challenging the status quo and seeking a more efficient and effective way Rigorously measuring our performance to ensure maximum impact COMPASSIONATE AND RESPECTFUL Building and sustaining a community for all those affected by lung cancer Respectful of all people with lung cancer, caregivers, loved ones, medical professionals, donors, board members, and employees COLLABORATIVE Committed to being good partners and strategic collaborators to enable us to reach our goal more quickly and efficiently, including through our scientific endeavors TRANSPARENT Fiscally responsible and holding ourselves to the highest ethical standards

Mission: To facilitate global collaboration and fund world-class research, medical education, and treatment trials, that make a positive impact on the lives of people with ME/CFS, Long COVID and related diseases. Vision: Significantly improve patient outcomes while advancing a cure. Goals: Our primary goals are to: frame clear disease mechanisms and models; find effective treatments and diagnostic markers; increase accurate diagnoses; and ensure access to quality care.

Our mission is to facilitate, advocate and promote education, support and research for the prevention, treatment and cure of liver disease.

Established in the year 2000, the Preeclampsia Foundation is a 501(c)(3) non-profit organization whose mission is to reduce maternal and infant illness and death due to preeclampsia and other hypertensive disorders of pregnancy by providing patient support and education, raising public awareness, catalyzing research and improving health care practices.