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The Gay and Lesbian Alliance Against Defamation (GLAAD) amplifies the voice of the LGBT community by empowering real people to share their stories, holding the media accountable for the words and images they present, and helping grassroots organizations communicate effectively. By ensuring that the stories of LGBT people are heard through the media, GLAAD promotes understanding, increases acceptance, and advances equality.

Founded in 2003, Transgender Legal Defense & Education Fund (TLDEF) is committed to ending discrimination based upon gender identity and expression and to achieving equality for transgender people through test-case litigation, public education, direct legal services, community organizing and public policy efforts. In 2024, TLDEF merged with National Center for Transgender Equality (EIN 41-2090291) to form a new organization, Advocates for Trans Equality. The new organization will use NCTE's old EIN until it has its own tax-exempt determination from the IRS.

The Los Angeles LGBT Center (formerly L.A. Gay and Lesbian Center) exists to: EMPOWER people to lead full and rewarding lives without limits based on sexual orientation and gender identity, by providing the highest quality educational, cultural, and wellness programs to residents of Los Angeles County; HEAL the damage caused by discrimination based on sexual orientation and gender identity, by providing the highest quality health and social services to residents of Los Angeles County in need; ADVOCATE full access and equality for all people regardless of sexual orientation or gender identity, by promoting our communities' needs at local, state, and national levels; and LEAD through example, by living our values, sharing our expertise, and celebrating the full diversity of our lives, families, and communities.

The Human Rights Campaign envisions an America where lesbian, gay, bisexual and transgender (LGBT) people are ensured of their basic equal rights, and can be open, honest and safe at home, at work and in the community. The HRC Foundation was established in 1986 as a non-political, tax-exempt organization. Through innovative outreach, education, advocacy and research, the HRC Foundation focuses on the policies, issues and practices that affect LGBT individuals and their families including health care, parenting, adoption, schools, family law, employment, coming out, religion and faith, civil unions and marriage, financial planning, minority-specific concerns and senior health and housing. The HRC Foundation is one of the nation's most respected sources of information on LGBT issues and its resources are utilized throughout the LGBT community as well as among policy-makers, corporate executives, religious and community leaders, elected officials, journalists, researchers and the media.

This fund support women’s reproductive rights to choose if and when to become a mother. All donations made will be split evenly among following verified 501(c)3 organizations: Plan C transforms access to abortion in the US by normalizing the self-directed option of abortion pills by mail. The Afiya Center acts to ignite the communal voices of Black womxn resulting in our full achievement of reproductive freedom. WRAAP assists women who are financially unable to pay for safe, legal abortions or emergency contraceptives. M + A Hotline is free & staffed by medical professionals offering support to self-managing miscarriage or abortions. National Network of Abortion Funds builds power with members to remove financial and logistical barriers to abortion access by centering people who have abortions and organizing at the intersections of racial, economic, and reproductive justice.

Genders and Sexualities Alliance Network (GSA Network) is a next-generation LGBTQ racial and gender justice organization that empowers and trains trans, queer, and allied youth leaders to advocate, organize, and mobilize an intersectional movement for safer schools and healthier communities. In California, GSA Network connects over 1,000 GSA clubs through regional summits and youth councils. Nationally, GSA Network leads the National Association of GSA Networks which unites 40 statewide networks of GSA clubs, and GSAs Unite, an online campaign and petition platform supporting youth organizers across the country.

Lexington Pride Center celebrates and empowers the intersectional lives of LGBTQIA+ Kentuckians. We envision a world free of marginalization, where every LGBTQIA+ person is safe to be who they are and love who they love.

The mission of Project Angel Food is to nourish the body and spirit of men, women, and children affected by HIV/AIDS, cancer, and other life-threatening illnesses. Our goal is to make sure no one in our community suffers the ravages of hunger and malnutrition while struggling with serious illnesses. Without our daily meal deliveries, clients risk malnutrition and deteriorating health since they are unable to provide their own meals. Project Angel Food acts with urgency as hunger and illness do not wait.