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Nancy G. Brinker promised her sister that she would do everything in her power to end breast cancer forever. That promise is now Susan G. Komen for the Cure®, the global leader of the breast cancer movement, having invested more than $2.2 billion since inception in 1982. As the world’s largest grassroots network of breast cancer survivors and activists, we’re working together to save lives, empower people, ensure quality care for all and energize science to find the cures. Thanks to events like the Susan G. Komen Race for the Cure® and the Susan G. Komen 3-Day for the Cure®, and generous contributions from our partners, sponsors and fellow supporters, we have become the largest source of nonprofit funds dedicated to the fight against breast cancer in the world.

Memorial Sloan-Kettering Cancer Center is dedicated to leading the fight against cancer, individually focusing on each patient and creating an impact on cancer treatment and the biomedical research agenda around the world. As one of the world's premier cancer centers, Memorial Sloan Kettering Cancer Center is committed to exceptional patient care, leading-edge research, and superb educational programs. The close collaboration between its physicians and scientists is one of its unique strengths, enabling it to provide patients with the best care available today as we work to discover more effective strategies to prevent, control, and ultimately cure cancer in the future.

From the website: "Miriam's House is a sober living transitional home for women and their children. Miriam's House opened its doors in 2007 to better serve mothers in recovery. Our unique program allows for mothers to get the help they need while maintaining or recovering custody of their children. Our mission is to empower these families with the critical life skills needed for a substance-abuse free future. We fulfill our mission by providing the mothers and children with a safe and nurturing environment and comprehensive social services." Miriam's House was formerly known as Promises Foundation.

YGB specializes in finding permanent families for young adults, teens, and pre-teens in foster care. We believe that no child should age out of the foster care system without the support and love of a family. Whether that means helping youth reconnect to their families of origin, to other people who have played a role in their lives, or to new families that will make a new commitment to be there for life. We recruit, train, certify and license parents who are willing to make an unconditional lifetime commitment. Likewise, we commit to providing ongoing support for our families for as long as they need. To honor his legacy, Discovery Inc. established the The Willie Garson Fund at You Gotta Believe to support our work of connecting every child in foster care to a loving family that commits to being there for life. The fund directly supports our Nobody Ages Out initiative, providing the services and resources needed to ensure their profound journey to becoming a family is a success.

It is the mission of Shriners Hospitals for Children to: -Provide the highest quality care to children with neuromusculoskeletal conditions, burn injuries and certain other special health care needs within a compassionate, family centered and collaborative care environment -Provide for the education of physicians and other health care professionals -Conduct research to discover new knowledge that improves the quality of care and quality of life of children and families. This mission is carried out without cost to the patient or family, and without regard to race, color, creed, sex or sect.

For over 30 years, Best Friends Animal Society has been running the nation’s largest no-kill sanctuary for companion animals and building effective programs that reduce the number of animals entering shelters. The mission of Best Friends Animal Society is to bring about a time when there are No More Homeless Pets. The organization does this by helping end the killing in America's animal shelters through building community programs and partnerships all across the United States.

The Michael J. Fox Foundation is dedicated to finding a cure for Parkinson's disease through an aggressively funded research agenda and to ensuring the development of improved therapies for those living with Parkinson's today. The Foundation's focus is increasingly on clinical and translational research, crucial to making strides toward a cure and improved therapies for those living with Parkinson's today.

Our mission is to be a relentless force in building a world of strong, healthier lives, free of cardiovascular diseases and stroke. Our mission drives everything we do. We’re the nation’s leader in CPR education training. We help people understand the importance of healthy lifestyle choices. We provide science-based treatment guidelines to healthcare professionals to help ensure the best treatment for every patient, every time. We educate lawmakers, policy makers and the public as we advocate for changes to protect and improve the health of our communities.

An organization committed to transforming the way youth experience homelessness. We envision a world where every child can celebrate major life milestones, regardless of their financial background or living environment. Worthy of Love exists to create positive experiences and life-long memories for homeless youth and their families, by providing all-expenses-paid birthday parties to them as they navigate life's most challenging circumstances. Children and families who attend our parties are provided with meals, snacks, dessert, and a variety of exciting vendors to enjoy throughout the event. Our parties provide a safe environment for attendees and are secured and monitored by trained staff and security. Every child that attends our parties leaves with special gifts designed to inspire confidence and promote self-worth. Along with personalized birthday gifts, attendees receive school supplies, hygiene kits, and essential tools needed to thrive in day-to-day activities. Since 2013, Worthy of Love has thrown unforgettable birthday parties for over 10,000 children and teens experiencing homelessness in Los Angeles County.

In the wake of the tragic earthquake that affected Morocco on the evening of September, 8, 2023 we are launching a fundraising campaign in partnership with local entities, in order to help the victims rebuild and tackle mid to long term effects of this tragedy. Our focus starts with one village, Ouirgane, to have as much impact as possible, and we hope that with your solidarity we would be able to reach several others. Our first target is to fundraise $100,000. Who we are: Salim and Ismael have co-founded Onna, an AI company that delivers a product to the world’s largest companies like Apple, Meta, Netflix, Spotify, Airbnb, Nike and many more. Salim now lives in Marrakech and is building an AI academy with a campus in the Atlas Mountains. See https://www.pledge.to/atlas-united

Our mission is to educate and empower youth and young adults in the bicycle mechanic and specialty coffee service industries. Our vision is to see kids develop agency and flourish within positive relationships, healthy lifestyles, and skill development. Our goal is to combine industry leading programs and community networks to foster the next generation of riders, young professionals, and community leaders. Our why is that many of our youth face systemic challenges in moving forward toward dreams. By creating strategic partnerships and dynamic solutions barriers in the bike world and Native Reservation can be overcome. Since 2018 Silver Stallion has established or helped establish 14 middle school mountain bike P.E. programs in the region with Outride "Riding 4 Focus." Along with that effort the Stallion started the Gallup and Navajo-Diné Composite NICA middle and high school mountain bike teams Since 2019, in partnership and with continued support from Durango Devo, Silver Stallion established DEVO/CLUB Rides program with Gallup McKinley County Schools now taking place at 4 middle schools on the Navajo Nation (Thoreau, Crownpoint, Tohatchi, Navajo). During the Pandemic Silver Stallion established “Big Blue” Mobile Ride Center truck providing Free Bike Repair events, Park Tool School Education and Free Bikes 4 Kidz distribution in remote communities throughout the Navajo Nation. Silver Stallion is partnered with Project Bike Tech establishing and supporting high school mechanic programs throughout the region.

The National Multiple Sclerosis Society's mission is to cure multiple sclerosis while empowering people affected by multiple sclerosis (MS) to live their best lives. The organization pledges to accelerate cures through global leadership, and improve access to personalized, affordable, high-quality MS healthcare. It empowers people affected by MS to solve everyday challenges and strengthens the MS movement through more and deeper connections.