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Direct Relief improves the health and lives of people affected by poverty or emergency situations by mobilizing and providing essential medical resources needed for their care. Direct Relief works in all 50 U.S. states and in more than 90 countries to expand access to medicine and healthcare by equipping doctors and nurses with lifesaving medical resources.

GlobalGiving makes it possible for anyone to give to community-led nonprofits all over the world. Our mission is to transform aid and philanthropy to accelerate community-led change. We make it possible for you to support local projects in 170 countries, giving nonprofits access to the funding, tools, and training they need to become more effective and to make our world a better place.

As the world's leading independent organization for children in need, Save the Children has programs in nearly 120 countries, including the United States. Their aim is to inspire breakthroughs in the way the world treats children, and to create immediate and lasting change in their lives by improving their health, education and economic opportunities. In times of acute crisis, Save the Children mobilizes rapid assistance to help children recover from the effects of war, conflict and natural disasters.

UNICEF's mission is to help very child thrive, all over the world. Over eight decades, it has built an unprecedented global support system for the world’s children. UNICEF relentlessly works day in and day out to deliver the essentials that give every child an equitable chance in life: health care and immunizations, safe water and sanitation, nutrition, education, emergency relief and more. UNICEF USA advances the global mission of UNICEF by rallying the American public to support the world’s most vulnerable children. Through advocacy, education and fundraising in the United States. The organization's Impact Fund for Children provides opportunities for social impact investors seeking to make a difference in the survival and development of children.

The American Red Cross prevents and alleviates human suffering in the face of emergencies by mobilizing the power of volunteers and the generosity of donors. The American Red Cross, through its strong network of volunteers, donors and partners, is always there in times of need. We aspire to turn compassion into action so that all people affected by disaster across the country and around the world receive care, shelter and hope; our communities are ready and prepared for disasters; everyone in our country has access to safe, lifesaving blood and blood products; all members of our armed services and their families find support and comfort whenever needed; and in an emergency, there are always trained individuals nearby, ready to use their Red Cross skills to save lives. The American Red Cross' fundamental principles are: Humanity, Impartiality, Neutrality, Independence, Voluntary Service, Unity, and Universality. Our motto, "You Have the Power to Save a Life" is built upon and reflects such these values.

CARE is a leading humanitarian organization fighting global poverty. We place special focus on working alongside poor women because, equipped with the proper resources, women have the power to help whole families and entire communities escape poverty. Women are at the heart of CARE's community-based efforts to improve basic education, prevent the spread of HIV, increase access to clean water and sanitation, expand economic opportunity and protect natural resources. CARE also delivers emergency aid to survivors of war and natural disasters, and helps people rebuild their lives.

Global Empowerment Mission (GEM) acts as a first responder to vulnerable communities affected by disasters around the world. GEM is dedicated to restoring hope and opportunity in the lives of those most affected by disasters. The organization provides immediate relief, assists communities during the gap period before receiving assistance from other institutions, and engages in long-term recovery efforts with sustainable development practices. This three-phased approach allows GEM to provide individuals and families with the help they need when they need it most.

The International Rescue Committee responds to the world's worst humanitarian crises, helping to restore health, safety, education, economic wellbeing, and power to people devastated by conflict and disaster. Founded in 1933 at the call of Albert Einstein, the IRC is at work in over 50 countries and more than 20 U.S. cities helping people to survive, reclaim control of their future and strengthen their communities. Over the past 90 years, the IRC has built a strong position as the largest refugee resettlement agency in the United States, and has paid close attention and provided service to the recent conflicts in Afghanistan (providing education and protection to 1 million Afghan citizens including women and girls) and Ukraine (collaborating with nonprofit organizations in both Ukraine and refugee-receiving Poland to provide aid).

The Stephen Siller Tunnel to Towers Foundation is to honor the sacrifice of firefighter Stephen Siller who laid down his life to save others on September 11, 2001. We also honor our military and first responders who continue to make the supreme sacrifice of life and limb for our country.

Right now, young trans people, particularly Black and Brown trans youth, are under attack across the country and around the world. The COVID-19 pandemic has exacerbated unsafe conditions for trans youth who are houseless, in foster care, in detention, and in abusive or otherwise unsafe housing situations. We want to show trans young people that they are loved, supported, and have a family of people around the world who care about them and want them to succeed. Anyone can be a Santa, join us! Transness is so beautiful and we are celebrating our magic! Deliver gifts anonymously to trans youth in need, safely.

YGB specializes in finding permanent families for young adults, teens, and pre-teens in foster care. We believe that no child should age out of the foster care system without the support and love of a family. Whether that means helping youth reconnect to their families of origin, to other people who have played a role in their lives, or to new families that will make a new commitment to be there for life. We recruit, train, certify and license parents who are willing to make an unconditional lifetime commitment. Likewise, we commit to providing ongoing support for our families for as long as they need. To honor his legacy, Discovery Inc. established the The Willie Garson Fund at You Gotta Believe to support our work of connecting every child in foster care to a loving family that commits to being there for life. The fund directly supports our Nobody Ages Out initiative, providing the services and resources needed to ensure their profound journey to becoming a family is a success.

The mission of Planned Parenthood is to provide comprehensive reproductive and complementary health care services in settings that preserve and protect the essential privacy and rights of each individual; to advocate public policies which guarantee these rights and ensure access to such services; to provide educational programs which enhance understanding of individual and societal implications of human sexuality; to promote research and the advancement of technology in reproductive health care and encourage understanding of their inherent bioethical, behavioral, and social implications.