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The core mission of the IRSF is to fund research for treatments and a cure for Rett syndrome while enhancing the overall quality of life for those living with Rett syndrome by providing information, programs, and services. In 1983, a small dedicated group of parents whose children had Rett syndrome formed the first non-profit to focus exclusively on Rett syndrome – International Rett Syndrome Association (IRSA). In 2007, IRSA and Rett Syndrome Research Foundation (RSRF) consolidated resources to better serve families and maximize research investments toward a cure. The International Rett Syndrome Foundation (IRSF) emerged with a mission to accelerate research and empower families that builds upon these foundations’ pioneering work toward care and cure. We are walking this journey with you. IRSF is comprised of parents and friends of those diagnosed with Rett syndrome. We are dedicated to empowering families with the latest medical information, offering meaningful support and resources, and advocating for all those living with Rett syndrome. Our strategy is simple but powerful: improve care today and create treatments for tomorrow. IRSF is committed to a full-spectrum approach, providing solutions for everyone living with Rett syndrome. We do this by investing in innovative research, working to build a robust treatment pipeline, and removing barriers to ensure clinical trial success.

Medical Missions for Children is dedicated to serving the medical needs of catastrophically ill children in underserved U.S. and international communities. Through the use of its Global Telemedicine and Teaching Network, a satellite and Internet-based communications platform, Medical Missions for Children facilitates the real-time treatment of remote, critically ill children, broadcasts an extensive program of continuing medical education, and supports dialogue exchange among a global network of medical specialists. The organization's goals are designed to help catastrophically ill children by raising the level of medical expertise in local hospitals in underserved areas through medical education for physicians, nurses, and hospital administrators and through the use of live, two-way diagnostic and treatment consultations between specialists based at major U.S. medical centers and physicians in the local hospital. Typically, Medical Missions for Children facilitates the treatment of 1,500 children each month. Medical Missions for Children's global network encompasses pediatric healthcare facilities in Latin America, Africa, India, and Eastern Europe, and the volunteer services of more than 22 tier-one U.S.-based and four international medical institutions. Medical Missions for Children also partners with the United Nations and the World Bank, serving as the exclusive content provider for its Global Development & Learning Network (delivered to universities, medical schools, and the World Bank's own Learning Centers). Medical Missions for Children's medical activities are carried out daily through the Global Telemedicine & Teaching Network(GTTN). The GTTN enables the pairing of physicians located at one or more of Medical Missions for Children's mentor medical centers with attending physicians located at its recipient hospitals. This relationship, established in a video-teleconference format, allows for the collaborative examination, diagnosis, and treatment of a child or pregnant woman in a real-time setting, resulting in a more comprehensive evaluation and accelerated treatment of a myriad of illnesses and physical conditions. Medical Missions for Children also addresses developing countries' pediatric and maternal healthcare concerns through the implementation of a multi-disciplinary medical education program. Tapping into the expertise of its volunteer medical centers, leading medical associations, and the National Institutes of Health, Medical Missions for Children manages and broadcasts a world-class digital library of medical education materials, including live and pre-recorded lectures, symposia, grand rounds, and research seminars. Medical Missions for Children, in partnership with St. Joseph's Children's Hospital, a 120-bed hospital in inner-city Paterson, New Jersey, manages a unique healing experience for its young patients. Giggles Theater, a 70-seat theater also able to accommodate children in wheelchairs and beds, and located within St. Joseph's Children's Hospital, brings local and regional performing artists directly to pediatric patients, through weekly performances and hands-on activities. Music, drama, puppetry, dance, storytellers, and live, interactive "video field trips" break the monotony and bring brightness to these sick children. Performances take place for both a live audience, and for non-ambulatory patients, broadcast via the hospital's closed circuit television system. Since the theater features the latest telecommunications technology Medical Missions for Children and St. Joseph's Children's Hospital transmit around the world to children's hospitals in developing countries.

Roseville Community Health Foundation affiliated with Sutter Roseville Medical Center in 2003 and changed it's name to Sutter Roseville Medical Center Foundation to more closely align itself with the medical center. Our mission is to cultivate partners and resources to provide state-of-the art medical services for our community with dignity and compassion.

The mission of Hands of Grace Medical Clinic is to ensure that the medically underserved and uninsured have access to quality health care.